The iconic X-shaped organization of metaphase chromosomes is frequently presented in textbooks and other media. The drawings explain in captivating manner that the majority of genetic information is ...

DNA does not float freely in the cell. Instead, it is wrapped around histone proteins to form structures called nucleosomes. These histones carry numerous chemical modifications that act as molecular ...

This provides us with a novel insight into the physical bases of mitotic chromosome condensation in living human cells," said Maeshima. "In this study, we discovered that mitotic chromosomes are ...

WORCESTER, MA – Using three dimensional modeling techniques, advanced computer simulation and next generation sequencing technology, faculty at the University of Massachusetts Medical School (UMMS) ...

Mitotic chromosomes are pivotal for the inheritance of genetic material. Now, it is already known that chromosomes vary in dimensions among organisms. But what governs mitotic chromosomal size and ...

In early cytological studies chromatids of metaphase chromosomes were suggested to coil into a spiral called chromonema. This assumption was recently supported by chromosomce conformation capture ...