Stanford University-led researchers report that tumor cells hijack mitochondria from immune cells, reducing anti-tumor immune function and activating cGAS-STING and type I interferon signaling that ...

Researchers have developed a new nanoparticle that can 'hitch a ride' on immune cells, or monocytes. Because of its tiny size, the particle can tag along directly into lymph nodes and help metastasis ...

Lymph nodes, hundreds of small structures located throughout the body, play a pivotal role in immunity, including anti-tumor immune responses. White blood cells, also known as lymphocytes, reside in ...

Lymph nodes aren't just passive waiting rooms for immune cells, they actively train and educate T cells, and send them off to do their job." Axel Kallies, Professor, Laboratory Head, Doherty Institute ...

The research group of Prof. Sanjiv Luther at the Department of Immunobiology of the University of Lausanne has discovered that a fibroblast subtype is essential for coordinating certain immune cells ...

Chimeric antigen receptor T-cell therapy, or CAR-T, has transformed treatment for blood cancers. The immunotherapy involves reprogramming a patient's own immune cells to recognize and attack tumor ...

March 2, 2026 – A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune ...

On the top, the schematic illustration shows the structure of scaffold, the seeding and proliferation of CAR-T cells within the scaffold after intratumor injection. On the bottom are the ...

Summary: Researchers demonstrated that the success of anti-CTLA-4 immunotherapy against brain tumors does not depend on local ...

There are around 600 lymph nodes everywhere in the body, including the neck, under the jaw, underarms, groin, chest and ...