Formalin fixed paraffin-embedded (FFPE) tissue constitutes an enormous untapped resource for discovery, validation, and measurement of valuable biomarkers of disease progression, drug response, and ...

Purpose: To address some of the challenges facing the incorporation of array comparative genomic hybridization technology as a clinical tool, including archived tumor tissue, tumor heterogeneity, DNA ...

Bottom-up mass spectrometry–based proteomics relies on protein digestion and peptide purification. The application of such methods to broadly available clinical samples such as formalin-fixed and ...

Alexander Paping is a research associate at the Charité Universitätsmedizin Berlin (Germany) in the Division of ‘Experimental Obstetrics’ as well as a practicing obstetrician in the Department of ...

Mass spectrometry is a key tool for proteomics, but traditional sample preparation methods often limit its potential. Techniques such as laser capture microdissection, antibody-based enrichment and ...