Fighting aging reports that loss of myostatin mutations in mice produce extended life spans, but too much suppression of myostatin may remove that benefit due to the cardiac issues that can accompany ...

In mice, a high-fat diet (HFD) induces obesity, insulin resistance and myostatin production. We tested whether inhibition of myostatin in mice can reverse these HFD-induced abnormalities. C57BL/6 mice ...

Myostatin has been indirectly linked with bone turnover through its influence on muscle, but new evidence highlights a direct role for this transforming growth factor-β family member in inflammatory ...