Effective and efficient protein purification processes are essential in drug discovery and development. Affinity fusion tags are commonly used in protein purification due to their ability to enable ...

Recombinant protein expression in bacterial hosts, most notably Escherichia coli, underpins a vast array of research and industrial applications, from enzyme production to therapeutic biologics. The ...

A large-scale production of recombinant proteins is important for biopharmaceutical companies and other industries. Escherichia coli (E. coli) has been the most widely used recombinant protein ...

This article is based on a poster originally authored by Sunidhi Shetty, Narasimha Murthy Bandaru, Anna Moberg and Marco Manni, which was presented at ELRIG Drug Discovery 2024 in affiliation with ...

A recombinant protein is a protein made by genetically engineered cells rather than extracted directly from its natural source. Scientists insert the gene for the desired protein into a production ...

Making proteins for research or therapies often starts with cell-line development. In many applications, genetic engineering is used to optimize a cell line for producing high levels of the intended ...

Researchers created a DIA-MS atlas of 13,609 proteins across 2,856 samples from fetal, healthy adult, paired non-tumor, and ...

Nuclera (Cambridge, UK) is a biotech company that specializes in rapid protein expression and purification optimization at the benchtop. With the aim of streamlining the drug discovery process, ...

To enhance CAR T therapies, scientists are actively studying TCR signaling and T-cell exhaustion mechanisms to improve CAR T persistence and function. Additionally, there is a growing trend towards ...

The “dark proteome” includes uncharacterized proteins that may influence cancer growth, immune evasion, and therapy ...