Immune checkpoint inhibitors have reshaped cancer treatment over the past decade, but the same immune activation that shrinks tumors can also turn against healthy tissue, including the brain. A ...

For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor cell ...

Researchers have uncovered a previously hidden “internal brake” on immune cells that limits their ability to fight cancer, ...

Memory T cell therapy improves infection clearance after transplant, with 60% remission and strong safety outcomes in early ...

Immunotherapy has been one of the most transformative treatments for cancer patients in recent decades, shifting the emphasis ...

Scientists at Cincinnati Children's have identified how certain immune cells are molecularly programmed to respond faster ...

In a paradigm breaking study, Dr. Pavan Reddy, director of the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine (BCM) and his team, in collaboration with Drs. Arul Chinnaiyan, S ...

The immune system relies on complex interactions between cells to orchestrate effective responses against pathogens and tumours. Among these, T cells play a pivotal role through their ability to ...

SLAMF6 is an immune cell receptor whose function was not clear. Does it activate or inhibit cells? The results so far have been contradictory. Now, scientists at the Institut de Recherches Cliniques ...