Among the forms of monogenic macular degeneration, the most common is Stargardt disease. This disease is caused by mutations in the ATP-binding cassette transporter alpha 4 subunit (ABCA4) gene, ...

In genomes, three letters or bases of DNA encode an amino acid. Amino acids are then strung together by the cell to create proteins. There is some redundancy in that genetic code, but there are single ...

Modern HIV medicine is based on a common genetic mutation. Now, researchers have traced where and when the mutation arose—and how it protected our ancestors from ancient diseases. What do a ...

New structural variation sequencing reads long stretches of fetal DNA to pinpoint duplications, flips, and rearrangements, ...

Long-lived neurons in the brain are among the cells most vulnerable to the gradual accumulation of somatic DNA mutations, ...

Scientists have uncovered the first direct evidence that inherited genetics can strongly influence cancer risk and help determine how tumors develop over time. The results show that the genes a person ...

Rutgers study finds genetic mutations in rodents, making them resistant to urban poisons, complicating pest control ...

Genetic inheritance may sound straightforward: One gene causes one trait or a specific illness. When doctors use genetics, it’s usually to try to identify a disease-causing gene to help guide ...

Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide ...

Emily Kramer-Golinkoff can’t get enough oxygen with each breath. Advanced cystic fibrosis makes even simple things like walking or showering arduous and exhausting. She has the most common fatal ...

From Tama, Japan's most famous stationmaster calico cat, to the lasagna-loving, ginger Garfield, cats with orange fur are both cultural icons and beloved pets. But their distinctive color comes with a ...