Controlling drug-to-antibody ratio and scalable reactors are key to reliable antibody-drug conjugate manufacturing success.

Recent collaboration offers more heterogeneous, stable antibody drug conjugates of synthetic tubulin-binding agents shown to rapidly trigger cancer cell death. Targeted drug delivery remains a ...

Dr Ishwar Singh, Senior Lecturer, School of Pharmacy, University of Lincoln, UK discusses about his areas of research, their objectives and the evolving sphere of pharma research, with Lakshmipriya ...

Antibodies are widely employed in the quantification of antigens in complex biological samples. Using techniques such as Western blotting, ELISA, and immunohistochemistry researchers are able to ...

Unlike current approaches where bioconjugation is typically done following the manufacture of the monoclonal antibody and the cytotoxic drug, the new method begins with the antibody supernatants and ...

To adapt to changing environmental pressures, bacteria have developed various methods that allow them to uptake exogenous DNA and incorporate it into their own genomes. One of these processes is ...

Conjugation is the process by which one bacterium transfers genetic material to another through direct contact. During conjugation, one bacterium serves as the donor of the genetic material, and the ...