Autoantibodies are antibodies that target the body’s own antigens. These antigens may consist of proteins, nucleic acids, carbohydrates, or lipids expressed ubiquitously throughout the body or only in ...

A growing body of evidence suggests that long COVID (or post-COVID syndrome), a condition affecting more than 10% of people after a SARS-CoV-2 infection, may be driven by the immune system turning ...

A new study, published in the Journal of Experimental Medicine, shows that about 2% of the population develop autoantibodies against type 1 interferons, mostly later in life. This makes individuals ...

We discovered high-titer neutralizing autoantibodies against interleukin-10 in a child with infantile-onset inflammatory bowel disease (IBD), a phenocopy of inborn errors of interleukin-10 signaling.

Neutralizing autoantibodies against interleukin-10 can result in a phenocopy of monogenic defects of interleukin-10 signaling in children and may be associated with inflammatory bowel disease (IBD).