Darkened tongue spots, dark gums, and bronzed skin: here's what it could mean!
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L’iperpigmentazione può essere uno dei primi segnali del morbo di Addison, una forma di insufficienza surrenalica primaria spesso legata a un meccanismo autoimmune. L’aumento dell’ACTH stimola i melanociti attraverso i recettori MC1R, provocando un caratteristico colorito bronzeo, particolarmente evidente nelle pieghe palmari, nelle aree ...
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