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After years in neurosurgery, here’s my take. Ozempic, Wegovy, and Mounjaro (GLP-1–based medications) are not cosmetic drugs. They target metabolic disease — and metabolic disease directly impacts the brain. What high-quality trials show: • SELECT (NEJM, 2023): Semaglutide reduced major cardiovascular events in overweight/obese adults without diabetes. • SUSTAIN-6 (NEJM, 2016): Semaglutide reduced stroke risk in patients with type 2 diabetes. • SURPASS program (2021–2023): Tirzepatide produced su
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🦷 There’s a reason the countdown always wins. General anesthetics work by binding to GABA receptors in the brain, the same system responsible for slowing down neural activity, which forces neurons across the cortex to quiet at once and triggers loss of consciousness within seconds. Researchers at MIT recently described it as the brain losing “dynamic stability,” meaning no amount of willpower or focus can override it once the drug reaches the bloodstream. Even seasoned anesthesiologists say the
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