Capisci che il paziente non è un semplice paziente Il clopidogrel è un pro-farmaco antiaggregante piastrinico 🩸 che, per essere attivato e svolgere la sua azione cardioprotettiva, richiede una bioattivazione epatica mediata dall’enzima citocromo CYP2C19 🧪. L’omeprazolo, un comune inibitore della pompa protonica (IPP) utilizzato come gastroprotettore 🍏, agisce come un potente inibitore competitivo di questo specifico enzima 🛑. Se assunti contemporaneamente, l’omeprazolo blocca il CYP2C19, imp

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